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The study included patients over 80 years old admitted to an acute geriatric unit. Data on demographics, comorbidities, and medications were collected. Anticholinergic burden was calculated using three scales (ADS, ARS, ACB) at admission and discharge. Pharmacists collaborated in clinical interviews, medication reconciliation, and validation using STOPP/START criteria. The study found significant reductions in anticholinergic burden using ARS and ACB scales.
To determine variations in anticholinergic burden of long-term medication in acute geriatric patients undergoing standard geriatric-pharmaceutical practice between admission and discharge.
Standard geriatric-pharmaceutical practice including medication reconciliation, review, and deprescription recommendations using STOPP/START criteria.
Pharmacists and geriatricians
Patients over 80 years old admitted to the acute geriatric unit; exclusions included readmission within 3 months, palliative care, or death during hospitalization.
Anticholinergic burden using ADS, ARS, and ACB scales; number of drugs; statistical significance of burden reduction.
Significant reduction in anticholinergic burden of long-term medication during acute hospitalization episode.
Multidisciplinary collaboration and application of STOPP/START criteria contributed to reduction in anticholinergic burden.
Small sample size and retrospective design; benefits of burden reduction not measured.
The study was retrospective and single-centre with a small sample size. The potential benefits of reducing anticholinergic burden were not measured.